OBJECTIVE: To evaluate if ostomy care pathways improve outcomes for adults anticipating or living with an ostomy. DATA SOURCES: In this systematic review, the authors searched the MEDLINE, CINAHL, Cochrane Central, and EMBASE databases. STUDY SELECTION: Studies were included if they met the following criteria: written in English, targeted adults anticipating or currently living with an ostomy, evaluated the impact of two or more components of an ostomy care pathway, and included one or more of the pertinent outcomes (patient satisfaction, hospital length of stay, hospital readmission rates, and staff satisfaction). DATA EXTRACTION: Details recorded included design, setting, descriptions of intervention and control groups, patient characteristics, outcomes, data collection tools, effect size, and potential harms.