Best Practice Spotlight Organizations (BPSOs) are health-care and academic organizations selected by the Registered Nurses’ Association of Ontario (RNAO) through a request for proposals process to implement and evaluate the RNAO's best practice guidelines.

It is a dynamic partnership that focuses on making a positive impact on patient care though evidence-based practice. Requests for proposals are released every three years. The Best Practice Spotlight Organization (BPSO) initiative has been a great success. It provides support to organizations that have formally agreed to implement and evaluate multiple RNAO best practice guidelines over a three (3) year period.

First launched in 2003, the BPSO initiative is an off-shoot of the RNAO's Nursing Best Practice Guideline program which began in November 1999 and has since spread across Canada and to countries around the world.